Understanding Estrogen and its Effect on Cognition

Understanding Estrogen and its Effect on Cognition


I always said that I would like to see
estrogen 17-beta estradiol on the cover of Time magazine as the
molecule with the year because it does so many things it acts
on so many body systems. Surgery they have to protect them in a
sense from the cancer that they might get from the mutations is to have their ovaries removed and
ovaries carry a very important, they make a very important estrogen called 17 beta estradiol and that actually acts on the brain and so we want
to know what happens when the 17 beta estradiol is no longer being made by the ovaries People are told that after the
surgery they may have problems sleeping they might have night sweats they might
have sort of all the typical menopausal symptoms but I think
the expectation is that those will go away after time. But what we don’t know is what happens to other body systems that depend on
estrogen in in a long-term absence of estrogen. We’re finding with very, very
preliminary data that memory is affected by estrogen deprivation and we’re
seeing that over time that effect is more and more so the longer women go from the moment
of their surgery into old age, the estrogen deprivation
makes a difference so I would say what might be surprising to
people is that having your ovaries removed
before natural menopause and is perhaps a very
different state then at then as if you just went into menopause naturally. The long-term big hope for this is
that some very smart biophysics student will design really a good imaging system so that we
can follow the ovaries over time and we can know when a woman might be getting ovarian
cancer at this stage it which can still be treated.

Leave a Reply

Your email address will not be published. Required fields are marked *